If you think there has been an overdose, call your poison control center or get medical care right away. People with IDA have low blood levels of hemoglobin. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. <> It is usually given slowly over 2 to 5 minutes or as directed by your doctor. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. But for other people, their anemia may come back after Injectafer treatment. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. Evenbirth controlcan lead to severeside effectslike bloodclots. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. For example: Say you weigh 105 pounds (about 48 kilograms). You may wonder how Injectafer compares with other medications that are prescribed for similar uses. There are currently no generic forms of either drug. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Headache. But you kidneys need iron in order to make EPO. Drug class: Iron products. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. But some people have a delayed allergic reaction to certain drugs. Side effectswill last a very long time if the cause of them is not resolved. Things to remember when you fill your prescription. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Generics tend to cost less than brand-name drugs. 1 0 obj Mild side effects of Injectafer can include:*. Pain, swelling, or redness at the injection site may occur. You will be watched closely by your doctor for 30 minutes after each dose. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Medically reviewed by Sanjai Sinha, MD. Ask your doctor or healthcare provider if Venofer is the right choice for you. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. Consult the product instructions and your pharmacist for storage details. Find out what health conditions may be a health risk when taken with Venofer Vial Tell your doctor if you are taking iron supplements or other iron-based oral medications. The infusion will take between 15-30 minutes if it is given in. Do not share your drugs with others and do not take anyone else's drugs. (A medication class is a group of medications that work in a similar way.). Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). Does Venofer Vial interact with other drugs you are taking? For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Do not start, stop, or change the dose of any drug without checking with your doctor. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. I used to get a different type but my . The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. All rights reserved. Heart failure: Could a low sodium diet sometimes do more harm than good? These people may lose weight as their anemia improves because theyre more active. We comply with the HONcode standard for trustworthy health information. Sharing this information can help you avoid potential interactions. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Yes, in some cases it may. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. The Injectafer dosage your doctor prescribes will depend on your body weight. These effects typically last between 7 and 11 hours. Pain, swelling, or redness at the injection site may occur. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. This gives a total cumulative dose of 1,500 mg of Injectafer. 5 0 obj But for other people, doing so could lead to having too much iron in their body. This is why family members often have the same issues with drugs as others in theirfamily. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Venofer injection contains iron sucrose, a form of the mineral iron. Selected from data included with permission and copyrighted by First Databank, Inc. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. <> However, many people have no side effects or only have minor side effects. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Some people only need one treatment course of Injectafer. Its given by either intravenous (IV) infusion or slow IV injection. Its because everyones body is different. treatment schedule in further detail. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. If needed, theyll recommend treatment, including certain medications. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Read all information given to you. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. The following information describes dosages that are commonly used or recommended. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. If you have symptoms of a low phosphorus level, call your doctor. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. experience severe side effects, please seek medical attention right away and notify the ordering physician. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Others last much longer (even a lifetime), which can be quite traumatizing to people. What are the side effects of Venofer? Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. This survey is being conducted by the WebMD marketing sciences department. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Below are examples of these side effects. These changes could help improve your anemia on a long-term basis. . The drug helps increase your hemoglobin level back to a value thats within the normal range. There may be drug take-back programs in your area. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Review our medical disclaimer. A shortage of iron can cause health problems. If these effects continue or worsen, tell your doctor. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. This document does not contain all possible drug interactions. The following lists contain some of the key side effects that may occur while taking Injectafer. You should not receive Venofer if you have known allergies to iron sucrose. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. A variety of tests can diagnose iron deficiency anemia. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Throw away unused or expired drugs. Serious side effects from Injectafer arent common, but they can occur. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. After the infusion, you can drive yourself home and return to your usual activities. Brand-name medications usually cost more than generics. Best food forward: Are algae the future of sustainable nutrition? An LSD comedown is when the mental and hallucinatory effects have worn . People with IDA have low blood levels of hemoglobin. Hemoglobin is a protein thats found in your RBCs. Depending on your doctors instructions and Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Orofer S 50 Injection 1 Injection in 1 Packet 147. Talk to your pharmacist for more details. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. This information should not be used to decide whether or not to take Venofer or any other medicine. Brand-name medications usually cost more than generics. Injectafer infusions are given over a period of at least 15 minutes. Or your doctor may recommend that you change your eating habits to include more iron in your diet. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. You may report side effects to FDA at 1-800-FDA-1088. They can tell you about other medications that may work well for you. VenAccess is a trademark of Vifor (International) Inc. Switzerland. administered at your doctors office or an infusion center. (A medication class describes a group of drugs that work in the same way.). Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Side effectsare uncomfortable reactions to medications or drugs. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. *Patients are calculated based on an estimated annual cumulative dose. Health careproviderscan provide information on how longside effectslast by checking amedication guide. * Sex and gender exist on spectrums. Discuss the risks and benefits with your doctor. Injectafer comes as a liquid solution inside vials. What Is the Cost of Whole Genome Sequencing (WGS)? Innovators Monograph Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. 2005 - 2023 WebMD LLC. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. However, side effects at the 150 mg dose may indicate that you might not . Injectafer is available only as a brand-name medication. A healthcare provider will give you this injection. fever. This means you would get two Injectafer doses of 720 mg each. 4 0 obj If you have diarrhea while youre taking Injectafer, call your doctor. Venofer treatment may be repeated if iron deficiency reoccurs. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). 2023 Medicine.com All rights reserved. Potential injection site discoloration has happened. During pregnancy, this medication should be used only when clearly needed. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. 2 0 obj For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. . Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Your healthcare provider will watch you closely for 30 minutes after each dose. Consult your doctor before breast-feeding. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. I hope you found answers and are feeling better now. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). I can't take oral supplements because they cause horrible debilitating Constipation. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Back pain. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. (And Injectafer is used to treat IDA.) This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. But for other people, their IDA returns after treatment with Injectafer. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. People from different ethnic backgrounds process medications differently. Dizziness. Joint pain. Phosphorus is an electrolyte that your body needs in order to make energy. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. The iron released by this drug does pass into human breast milk. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). It can be given as a slow injection over 2 to 5 minutes or as an infusion. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. These are not all of the side effects that may occur. Do not exceed 1,500 mg of iron per dosing course. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Keep all medications away from children and pets. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. (IV iron is absorbed by the body more rapidly than oral iron.) Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Injectafer is a brand-name prescription drug. They have been a god send. Injectafer begins working as soon as it enters your body. WebMD provides common contraindications for Venofer Vial. Injectafer and Venofer can cause very similar side effects, but some different ones as well. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Last reviewed . 2. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. During Injectafer treatment, your doctor will likely order blood tests. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. It's a more immediate treatment than supplements or dietary changes. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Theseside effectscan range from being mild tosevere. This website is intended for use by US healthcare professionals only. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Venofer® (iron sucrose injection, USP) is available by prescription only. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Allergic reactions typically occur the first time your body is exposed to a drug. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. Theyll recommend how to manage your condition. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
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